There is a big weight loss debate over the effectiveness of a low-carbohydrate diet and a low-fat diet. A new study has discovered that a low-carb diet is more effective at reducing fat and insulin resistance among the obese participants. 

Recently, in the World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease, Dr. Tracey McLaughlin, a professor of medicine, endocrinology, gerontology, and metabolism at Stanford University, explained how fat-cell sizes create an impact on our health. His research revealed the importance of fat cell size in losing weight. 

DIETFITS, a controlled trial compared low-fat and low-carb diets with the same amount of calories during weight loss and removing sugar, refined grains, and processed food intake. The results were published in 2018 and showed the weight loss figure was the same. But the biopsied fat cells of the 40 overweight participants have different results after 6 months of dieting:

  • The low-carb participants had a reduction in fat cell size and significantly lower circulating insulin levels, below 50 µU/mL

  • The low-fat group had no change in fat-cell size and significantly higher circulating insulin levels, peaking above 350 µU/mL.

Dr. McLaughlin concluded that when you have smaller fat cells, your metabolic health improves tremendously. He showed how the size of fat cells can predict the insulin resistance of an individual. He said that the more weight you lose, the better insulin action becomes and the more your fat-cell size shrinks. 

Another study conducted by Dr. Sarah Hallberg, of Virta Health, shared the benefits of a very low-carb diet (ketogenic style). Keto diet can improve blood sugar control, reverse diabetes, and reduce cardiovascular risk scores for heart disease. In her study, she noted that in 2 years, 91% of participants had reduced or eliminated their insulin use with 55% in remission from their diabetes.